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Contraindicated in patients with known or suspected gastrointestinal obstruction, including paralytic ileus; could cause spasm of sphincter of Oddi; opioids might cause increases in serum amylase; keep an eye on patients with biliary tract ailment, like acute pancreatitis, for worsening symptomsProlonged use during pregnancy may end up in neonatal

The oral bioavailability of morphine is somewhere around twenty to 40%. When morphine sulfate extendedrelease tablets are given on a hard and fast dosing regimen, regular-point out is attained in about a day.In India, opium harvested by licensed poppy farmers is dehydrated to uniform levels of hydration at government processing facilities, then off